The European Union has signed formal regional and urban policy cooperation agreements with: Brazil, Chile, Peru, Mexico, Colombia and Argentina.
In addition, it also has supra-national agreements in this area with organizations such as:
- Central American Integration System (SICA): whose members are Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama.
- Community of Latin American and Caribbean States (CELAC): which encompasses 33 countries in Latin America and the Caribbean.
Among the EU-Latin America cooperation projects the following stand out:
| NAME | DURATION | DESCRIPTION | THEME |
| AL-INVEST | 1994-2018 | Financing to improve the productivity and competitiveness of micro, small, and medium-sized enterprises in Latin America and fostering economic relations within the region and with the EU. | Urban Development |
| RED Project | 2010-2013 | Support in the process of building Regional Innovation Strategies in Chile | Regional innovation |
| URBELAC | 2011-2017 | Platform to promote exchanges between cities facing similar challenges through the exchange of knowledge, experiences, good practices and lessons learned and to conceive integrated development processes (31 cities) | Urban Development |
| International Urban Cooperation Program (IUC) | 2016-2019 |
Component 1 : Inter-city cooperation on sustainable urban development Component 2 : Cooperation between cities in actions related to climate change with a focus on sustainable energy, based on the experience of the Covenant of Mayors of the EU. Component 3: Cooperation between regions (sub-national entities) regarding innovation. |
1. Urban development 2. Urban development 3. Regional innovation |
| INNOVACT | 2017-2020 |
Based on the experience of the EU regional policy, it seeks to disseminate experiences and good practices, with special attention to cross-border areas:
|
Territorial cohesion |
| INNOV-AL | 2017-2020 |
Facilitate the pooling of information and lessons learned on promoting regional innovation systems, decentralized policies for innovation, competitiveness and smart specialization in Latin American countries:
|
Territorial cohesion |
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